|
| Thursday
Morning, October 17, 2002 |
| Morning
Session: |
Basic
Sciences and Animal Models in Bone Research |
| Moderators:
|
Ke HZ & Qin L / Chen D & Huang L |
|
| 08:30 |
Registration |
| 09:00 |
Opening
remarks |
Leung
PC ,
Ke HZ,
Chan KM , Genant HK, Dambacher MA, Qin L,
Leung KS ,
Cheng JCY |
| 09:10 |
Animal
models and study design for osteoporosis research |
Ke
HZ |
| 09:40 |
Goat
as an large osteoporotic animal model and enhancement of osteoporotic
bone fracture fixation using injectable "Bone Source" |
Leung
KS |
| 10:00 |
Genetically
engineered animal models as powerful tool for the study of osteoclast
biology |
Li
J |
| 10:20 |
Statistical
power analysis in clinical and experimental study design |
Li
W |
| 10:40 |
Tea
Break
|
| 11:00 |
Specific
regulation of BMP-2 gene expression by NF- B
in growth plate chondrocytes |
Chen
D |
| 11:20 |
Studies
on the roles of the dentin matrix protein 1 in bone biology
- Give insights into mechanism of mineralization and how bone
responds to mechanical loading |
Harris
SE |
| 11:40 |
Systemic
TNFa promotes erosive bone resorption by increasing the number
of CD11b+ osteoclast progenitors in the periphery which are
dependent on RANK signaling for osteoclastogenesis |
Xing
LP |
| 12:00 |
Osteoporosis
and related genes |
Xu
Y |
| 12:20 |
Genomics
and drug discovery |
Ji
XH |
| 12:40 |
Lunch
|
|
| Thursday
Afternoon, October 17, 2002 |
| Afternoon
Session: |
Prevention
and treatment of Osteoporosis, Osteoporotic Fracture Fixation,
Biomaterials and Biophysical Intervention |
| Moderators:
|
Dambacher MA & PC Leung / Cheng JCY & Wang M |
|
| 14:00 |
Individual
course of bone density evaluated in patients treated with bisphosphonates,
estrogens, calcitonin and SERMs |
Dambacher
MA |
| 14:30 |
Application
of Chinese herbs to primary osteoporosis: Comprehensively improving
the bone quality |
Shi
YY |
| 14:50 |
R&D
of herbal formulae for prevention and treatment of osteoporosis |
Qin
L |
| 15:10 |
Bone
structures in vivo und in vitro of osteoporotic patient |
Neff
M |
| 15:30 |
Pathophysiolgy
of microdamage |
Mori
S |
| 15:50 |
Osteoporotic
fractures and related clinical problems |
Leung PC |
| 16:10 |
Fixation
of osteoporotic spine |
Lu
WW |
| 16:30 |
Tea
Break |
| 16:50 |
Vibration
for prevention of osteoporosis |
Schiessl
H |
| 17:10 |
Low-frequency
ultrasound on human periosteal cells and fracture healing |
Cheung
WH |
| 17:30 |
Low-frequency
ultrasound for acceleration of bone-tendon junction repair |
Qin
L |
| 17:50 |
Shockwave
and bone regeneration |
Guo
X |
| 18:10 |
Biomaterials
in Orthopaedics |
Wang
M |
| 18:30 |
Bone-biomaterial
interface studies from basic science to clinical application |
Cheng
JCY |
| 19:30 |
Banquet |
|
| Friday
Morning, October 18, 2002 |
| Morning
Session: |
Biotechnologies
in Bone Research / Research opportunities & collaboration |
| Moderators:
|
Jiang YB & Qin L |
|
| 09:00 |
Overviews
of advances in bone mineral density measurement and diagnostic
dilemmas in osteoporosis assessment |
Genant
HK |
| 09:30 |
Pediatric
densitometry |
Schönau
E |
| 09:50 |
Bone
histology, histomorphometry, and microCT in experimental and
clinical studies |
Jiang
YB |
| 10:10 |
Application
of confocal microscopic technologies and imange analysis in
bone research |
Lee
KM |
| 10:30 |
Tea
Break |
| 10:50 |
Podium
discussion
- Important information resources and their web address for
bone research (Qin L)
- Research societies and research opportunities (Jiang YB)
- Training and education (Leung KS / Ke HZ, Chan KM)
- 2004 Xian Conference ( Ke HZ / Ji XH)
- Research collaboration and research grant application (All)
- Souvenir presentation
|
Genant
HK,
Dambacher A,
Ke HZ,
Leung KS,
Qin L,
Chan KM,
Leung PC
|
| 11:40 |
-
Photo Taking
- Research Facilities Visit (LHS/JOCOC/Cancer Center) |
| 12:40 |
Lunch |
|
| Friday
Afternoon, October 18 to Saturday Afternoon, October 19, 2002 |
| Hands-on
Workshop (one and half day) |
| Guideline
: |
The
participants will select one of the following two hands-on workshops.
Technical talks and usersˇ¦ meeting are integrated into corresponding
hands-on workshops. |
|
| Friday
Afternoon, October 18, 2002 |
Hands-on
Workshop I : Bone molecular biology, hard tissue histomorphometry
Moderators: Harris & Lee KM |
| Technical
Talks ˇV Basic and Advanced Bone Molecular Biology |
| 14:00 |
Establishment
of knock-out animal models |
Harris
SE |
| 14:20 |
Characterization
of bone phenotype of gene altered animals |
Ke
HZ |
| 14:40 |
In
vivo local bone formation model: calvarial injection |
Chen,
D |
| 15:00 |
Evaluation
of gene expression by Real-Time Quantitative RT-PCR |
Huang
L |
| Users'
meeting - Free Papers |
| 15:20 |
A
clinical and experimental study of blood flow of femoral head
|
Yang
Bo et al. |
| 15:40 |
Cultivation
of osteoclast-like cell derived from spleen pluripotent stem
cell and its effects on osteoblast proliferation and function
|
LI
YM et al. |
| 16:00 |
Tea
Break |
| Techniques
of histology and histomrophometry in bone research |
| 16:20 |
Decalcified
bone tissue preparations |
Wu
HT |
| 16:40 |
-
In vivo florescence labeling,
- MMA embedding, Sectioning, grinding, and staining
- High resolution macroradiography and photometry of radiographs.
|
Chan
CW |
| 17:00 |
Image
Analysis for semi-quantitative measurement with immunohistochemistry |
Fu
SC |
| 17:20 |
Static
and dynamic bone histomorphometry |
Yeung
HY /
Jiang YB |
| 17:50 |
End |
Hands-on
Workshop II: Non-invasive Densitometry
Moderators: Hangartner T & Qin L |
| Technical
Talks ˇV Non-invasive Bone Mineral Density Measurement Techniques
and Biomaterials |
| 14:00 |
Analysis
of fine structures by computed tomography |
Hangartner
TN |
| 14:30 |
Management
of osteoporosis in primary care |
Irit
Y |
|
Users'
meeting - Free Papers |
| 14:50 |
Tissue
engineering scaffolds with heterogeneous materials |
Zheng
WG et al. |
| 15:10 |
Assessment
on A-P DXA results of lumbar spine |
Fan
HB et al. |
| 15:30 |
An in vitro biomechanical evaluation of two polymethy-
methacrylate cements for use in vertebroplasty |
Wang
XY et al. |
| 15:50 |
Tea
Break |
|
Technical
talks and hands on demonstration on Bone Densitometry |
| 16:10 |
-
Dual energy X-ray absormetry (DXA)
- Peripheral quantitative computed tomography (pQCT)
- Quantitative ultrasound (QUS) |
Hung
VWY
Au SK
Choy WY |
| 17:30 |
End |
|
| Saturday,
October 19, 2002 |
Hands-on
Workshop I : Hand-on and Demonstration of Histology and
Histomorphometry
Coordinators: Chan CW / Yeung HY |
| 09:00 |
Decalcified
bone histology |
Wu
TH |
| 09:30 |
Undecalcified
bone histology
- In vivo florescence labeling
- MMA embedding, saw microtome and heavy duty microtome sectioning,
grinding, and staining
- High resolution macroradiography and photometry of radiographs.
|
Chan
CW |
| 10:30 |
Image
Analysis for semi-quantitative measurement with immunohistochemistry |
Fu
SC |
| 10:50 |
Static
and dynamic bone histomorphometry
- Bone Histomorphometry (OsteoMeasureTM)
- MicroCT (Scanco Łg40) |
Yeung
HY /
Jiang YB |
| 11:50 |
Application
of laser scanning confocal microscopy in bone research (Zeiss
LSM 510) |
Lee
KM |
| 12:40 |
Lunch |
| 14:00 |
Individual
request for related techniques, with the possibility of exchanges
of participants between Workshop I and Workshop II |
All |
| 17:00 |
End |
Hands-on
Workshop II: Non-invasive Densitometry and Biomechanical
testing
Moderators: Lu WW / Chow DHK
Coordinators: Siu SW / Chong WS |
| Tissue
Biomechanics |
| 09:00 |
Basics
in hard tissue biomechanics |
Chow
DHK |
| 09:30 |
Contact
microradiography, acoustic microscopy, and nano-indentation |
Qin
L |
| 10:00 |
The
study of biomechanical property and biochemical content of articular
cartilage in osteoarthritic rabbit |
Cao
YL |
| 10:20 |
Tea
Break |
| 11:40 |
- Sample preservation and preparation
- Selection of testing jigs for fixation, testing methods, and
testing conditions
- Factors influencing testing results,
- Interpretation of the testing results
|
Chow
D
Lu WW
Siu SW
Chong WS |
| 12:40 |
Lunch |
| 14:00 |
Individual
Request for Related techniques, with the possibility of exchanges
of participants between Workshop I and Workshop II |
All |
| 17:00 |
End |
|
|
